Compile Data Set for Download or QSAR
maximum 50k data
Found 4 of ic50 data for polymerid = 1884
TargetDihydrofolate reductase(Streptococcus pneumoniae)
Gsk

LigandPNGBDBM18070(5-[(2-cyclopropyl-7,8-dimethoxy-2H-chromen-5-yl)me...)
Affinity DataIC50:  8nMpH: 7.0 T: 2°CAssay Description:Activity was measured as a change in absorbance over time at a wavelength of 340 nm (A340), so as to monitor the disappearance of NADPH. After incuba...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetDihydrofolate reductase(Streptococcus pneumoniae)
Gsk

LigandPNGBDBM18071(5-chloro-3-({4-[(2,4-diaminopyrimidin-5-yl)methyl]...)
Affinity DataKi:  27nM ΔG°:  -10.5kcal/mole IC50:  50nMpH: 7.0 T: 2°CAssay Description:Activity was measured as a change in absorbance over time at a wavelength of 340 nm (A340), so as to monitor the disappearance of NADPH. After incuba...More data for this Ligand-Target Pair
In DepthDetails
TargetDihydrofolate reductase(Streptococcus pneumoniae)
Gsk

LigandPNGBDBM18069(5-[(3,4,5-trimethoxyphenyl)methyl]pyrimidine-2,4-d...)
Affinity DataIC50:  75nMpH: 7.0 T: 2°CAssay Description:Activity was measured as a change in absorbance over time at a wavelength of 340 nm (A340), so as to monitor the disappearance of NADPH. After incuba...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetDihydrofolate reductase(Streptococcus pneumoniae)
Gsk

LigandPNGBDBM18069(5-[(3,4,5-trimethoxyphenyl)methyl]pyrimidine-2,4-d...)
Affinity DataKi:  240nM ΔG°:  -9.18kcal/mole IC50:  3.00E+3nMpH: 7.0 T: 2°CAssay Description:Activity was measured as a change in absorbance over time at a wavelength of 340 nm (A340), so as to monitor the disappearance of NADPH. After incuba...More data for this Ligand-Target Pair
In DepthDetails